MySQL cuenta con dos uniones
select
t.Topic,
t.Title,
s.StarCount,
m.UserCount,
m.MessageCount
from
Topics t
left join (
select
Topic,
count(distinct User) as UserCount,
count(*) as MessageCount
from Messages
group by Topic
) m ON m.Topic = t.Topic
left join (
select
Topic,
count(*) as StarCount
from Stars_Given
group by Topic
) s ON s.Topic = t.Topic
Vinay Babu