df.rename(columns={'oldName1': 'newName1',
'oldName2': 'newName2'},
inplace=True, errors='raise')
# Make sure you set inplace to True if you want the change
# to be applied to the dataframeimport pandas as pd
data = pd.read_csv(file)
data.rename(columns={'original':'new_name'}, inplace=True)df = df.rename(columns = {'myvar':'myvar_new'})df.rename(columns={"old_col1": "new_col1", "old_col2": "new_col2"}, inplace=True)df.rename(columns={"old_col1": "new_col1", "old_col2": "new_col2"})df = df.rename(columns={'oldName1': 'newName1', 'oldName2': 'newName2'})
# Or rename the existing DataFrame (rather than creating a copy)
df.rename(columns={'oldName1': 'newName1', 'oldName2': 'newName2'}, inplace=True)